Photodiagnosis and Photodynamic Therapy
Volume 2, Issue 2 , Pages 149-155 , June 2005

An ultrasound analysis of the response of Gorlin syndrome-related and sporadic basal cell carcinomas to aminolaevulinic acid photodynamic therapy

  • Juliette A. Loncaster, MD, FRCR

      Affiliations

    • Department of Clinical Oncology, Christie Hospital (NHS) Trust, Wilmslow Road, Manchester M20 4BX, UK
    • Corresponding Author InformationCorresponding author. Tel.: +44 161 446 3678; fax: +44 161 446 3334.
    • ,
  • James V. Moore

      Affiliations

    • Department of Clinical Oncology, Christie Hospital (NHS) Trust, Wilmslow Road, Manchester M20 4BX, UK
    • ,
  • Donald Allan

      Affiliations

    • North Western Medical Physics, Christie Hospital (NHS) Trust, Manchester M20 4BX, UK
    • ,
  • Ernest Allan

      Affiliations

    • Department of Clinical Oncology, Christie Hospital (NHS) Trust, Wilmslow Road, Manchester M20 4BX, UK

References 

  1. Gorlin RJ, Goltz RW. Multiple nevoid basal-cell epithelioma, jaw cycsts and bifid rib syndrome. N Engl J Med. 1960;262:908–912
  2. Gorlin RJ. Nevoid basal cell carcinoma syndrome. Dermatol Clin. 1995;13:113–125
  3. Evans DG, Farndon PA, Burnell LD, Gattameni HR, Birch JM. The incidence of Gorlin syndrome in 173 consecutive cases of medulloblastoma. Br J Cancer. 1991;64:959–961
  4. Farndon PA, Del Mastro RG, Evans DG, Kilpatrick MW. Location of gene for Gorlin syndrome. Lancet. 1992;339:581–582
  5. Cowan R, Hoban P, Kelsey A, Birch JM, Gattamaneni R, Evans DG. The gene for the nevoid basal cell carcinoma syndrome acts as a tumor-suppressor gene in medulloblastoma. Br J Cancer. 1997;76:141–145
  6. Evans DG, Birch JM, Orton CI. Brain tumors and the occurrence of severe invasive basal cell carcinoma in first degree relatives with Gorlin syndrome. Br J Neurosurg. 1991;5:643–646
  7. O’Malley S, Weitman D, Olding M, Sekhar L. Multiple neoplasms following craniospinal irradiation for medulloblastoma in a patient with nevoid basal cell carcinoma syndrome. Case report. J Neurosurg. 1997;86:286–288
  8. Walter AW, Pivnick EK, Bale AE, Kun LE. Complications of the nevoid basal cell carcinoma syndrome: a case report. J Pediatr Hematol Oncol. 1997;19:258–262
  9. Atahan IL, Yildiz F, Ozyar E, Uzal D, Zorlu F. Basal cell carcinomas developing in a case of medulloblastoma associated with Gorlin's syndrome. Pediatr Hematol Oncol. 1998;15:187–191
  10. Applegate LA, Goldberg LH, Ley RD, Ananthaswamy HN. Hypersensitivity of skin fibroblasts from basal cell nevus syndrome patients to killing by ultraviolet B but not by ultraviolet C radiation. Cancer Res. 1990;50:637–641
  11. Karrer S, Szeimies RM, Hohenleutner U, Heine A, Landthaler M. Unilateral localized basaliomatosis: treatment with topical photodynamic therapy after application of 5-aminolaevulinic acid. Dermatology. 1995;190:183–185
  12. Kopera D, Cerroni L, Fink-Puches R, Kerl H. Different treatment modalities for the management of a patient with the nevoid basal cell carcinoma syndrome. J Am Acad Dermatol. 1996;34:937–939
  13. Rifkin R, Reed B, Hetzel F, Chen K. Photodynamic therapy using SnET2 for basal cell nevus syndrome: a case report. Clin Ther. 1997;19:639–641
  14. Edwards C, Al-Aboosi MM, Marks R. The use of A-scan ultrasound in the assessment of small skin tumors. Br J Dermatol. 1989;121:297–304
  15. Fornage BD, McGavran MH, Duvic M, Waldron CA. Imaging of the skin with 20-MHz US. Radiology. 1993;189:69–76
  16. Moran CM, Bush NL, Bamber JC. Ultrasonic propagation properties of excised human skin. Ultrasound Med Biol. 1995;1177–1190
  17. Morton CA, MacKie RM, Whitehurst C, Moore JV, McColl JH. Photodynamic therapy for basal cell carcinoma: effect of tumor thickness and duration of photosensitiser application on response. Arch Dermatol. 1998;134:248–249
  18. Soler AM, Warloe T, Tausjo J, Berner A. Photodynamic therapy by topical aminolaevulinic acid, dimethylsulphoxide and curettage in nodular basal cell carcinoma: a one-year follow-up study. Acta Derm Venereol. 1999;79:204–206
  19. Peng Q, Soler AM, Warloe T, Nesland JM, Giercksky KE. Selective distribution of porphyrins in skin thick basal cell carcinoma after topical application of methyl 5-aminolevulinate. J Photochem Photobiol B. 2001;62:140–145
  20. Allan E, Pye DA, Levine EL, Moore JV. Non-invasive pulsed ultrasound quantification of the resolution of basal cell carcinomas after photodynamic therapy. Lasers Med Sci. 2002;17:230–237
  21. Seidenari S, Pagnoni A, Di Nardo A, Giannetti A. Echographic evaluation with image analysis of normal skin: variations according to sex and age. Skin Pharmacol. 1994;7:201–209
  22. Whitehurst C, Byrne K, Moore JV. Development of an alternative light source to lasers for photodynamic therapy: 1. Comparative in vitro dose response characteristics. Lasers Med Sci. 1993;8:259–267
  23. Haller JC, Cairnduff F, Slack G, et al. Routine double treatments of superficial basal cell carcinomas using aminolaevulinic acid-based photodynamic therapy. Br J Dermatol. 2000;143:1270–1275
  24. Fink-Puches R, Soyer HP, Hofer A, Kerl H, Wolf P. Long-term follow-up and histological changes of superficial nonmelanoma skin cancers treated with topical delta-aminolaevulinic acid photodynamic therapy. Arch Dermatol. 1998;134:821–826

PII: S1572-1000(05)00064-5

doi: 10.1016/S1572-1000(05)00064-5

Photodiagnosis and Photodynamic Therapy
Volume 2, Issue 2 , Pages 149-155 , June 2005

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