Photodiagnosis and Photodynamic Therapy
Volume 2, Issue 3 , Pages 235-238 , September 2005

The influence of intracellular mTHPC concentration upon photobleaching dynamics

  • M. Atif, MPhil PhD

      Affiliations

    • Department of Physical Sciences, University of Hull, Cottingham Road, Hull HU6 7RX, UK
    • Corresponding Author InformationCorresponding author. Tel.: +44 1482 465134.
    • ,
  • M.R. Stringer

      Affiliations

    • School of Medicine, Medical Physics, University of Leeds, UK
    • ,
  • J.E. Cruse-Sawyer

      Affiliations

    • School of Biochemistry and Molecular Biology, University of Leeds, UK
    • ,
  • P.E. Dyer

      Affiliations

    • Department of Physical Sciences, University of Hull, Cottingham Road, Hull HU6 7RX, UK
    • ,
  • S.B. Brown

      Affiliations

    • School of Biochemistry and Molecular Biology, University of Leeds, UK

References 

  1. Georgakoudi I, Nichols MG, Foster TH. The mechanism of Photofrin photobleaching and its consequence for photodynamic dosimetry. Photochem Photobiol. 1997;65:135–144
  2. Atif M, Stringer MR, Cruse-Sawyer JE, Brown SB. Fluence-rate effects upon mTHPC photobleaching in a formalin-fixed cell system. J Photodiagn Photodyn Ther. 2004;1(2):173–180
  3. Fuchs J, Thiele J. The role of oxygen in cutaneous PDT. Free Radical Biol Med. 1998;24:835–847
  4. Moan J, Streckte G, Bagdonas S, Bech O, Berg K. Photobleaching of PpIX in cells incubated with 5-ALA. Int J Cancer. 1997;70:90–97
  5. Bagdonas S, Ma LW, Iani A, Rotomskis R, Juzenas P, Moan J. Phototransformations of ALA induced PpIX in vitro: a spectroscopic study. Photochem Photobiol. 2000;72:186–192

PII: S1572-1000(05)00096-7

doi: 10.1016/S1572-1000(05)00096-7

Photodiagnosis and Photodynamic Therapy
Volume 2, Issue 3 , Pages 235-238 , September 2005

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