Photodiagnosis and Photodynamic Therapy
Volume 3, Issue 2 , Pages 106-111 , June 2006

Influence of non-irradiated and ultraviolet-A-irradiated N,N-dialanyl protoporphyrin and diarginine diprotoporphyrinate on the neutrophil respiratory burst in vitro

  • Andrzej Bugaj, PhD, Master of Pharmacy

      Affiliations

    • Departments of Clinical Pharmacy and Biopharmacy, Karol Marcinkowski University of Medical Sciences, ul. Marii Magdaleny 14, Poznań 61-861, Poland
    • Corresponding Author InformationCorresponding author. Tel.: +48 61 8529057x54; fax: +48 61 8529057x55.
  • ,
  • Hanna Billert

      Affiliations

    • Department of Experimental Anesthesiology, Karol Marcinkowski University of Medical Sciences, Poland
  • ,
  • Iwona Krawiec

      Affiliations

    • Departments of Clinical Pharmacy and Biopharmacy, Karol Marcinkowski University of Medical Sciences, ul. Marii Magdaleny 14, Poznań 61-861, Poland
  • ,
  • Sylwia Żądłowska

      Affiliations

    • Departments of Clinical Pharmacy and Biopharmacy, Karol Marcinkowski University of Medical Sciences, ul. Marii Magdaleny 14, Poznań 61-861, Poland

References 

  1. Moan J, Peng Q. An outline of the history of PDT. In:  Patrice T editors. Photodynamic therapy. Cambridge: The Royal Society of Chemistry; 2003;p. 9–11
  2. Allison RR, Downie GH, Cuenca R, Xin-Hua H, Childs CJH, Sibata CH. Photosensitizers in clinical PDT. Photodiagn Photodyn Ther. 2004;1:27–42
  3. Boyle RW, Dolphin D. Structure and action relationships of photodynamic sensitizers. Photochem Photobiol. 1996;64:469–485
  4. Oleinick NL, Evans HH. The photobiology of photodynamic therapy: cellular targets and mechanism. Radiat Res. 1998;150(Suppl.):146–156
  5. Coussens LM, Werb Z. Inflammation and cancer. Nature. 2002;420:860–867
  6. Kaffenberger W, Classen BP, Beuningen DV. The respiratory burst of neutrophils, a prognostic parameter in head and neck cancer?. Clin Immunol Immunopathol. 1992;64:57–62
  7. Gal D, Kriska T, Maltseva E. In vitro experimental studies on the role of free radicals generated in cell structures. Biochem Biophys Res Commun. 1997;233:173–176
  8. Williams M, Krootjes BH, Steveninck JV. The pro- and antioxidant properties of protoporphyrin IX. Biochim Biophys Acta. 1989;1211:310–316
  9. Afonso S, Vanore G, Batlle A. Protoporphyrin IX and oxidative stress. Free Radic Res. 1999;31:161–170
  10. Graczyk A, Konarski J. Hematoporphyrin derivatives complex salts and their use in the detection and treatment of neoplasms. 1997, European patent no. EPO539960B1.
  11. Bugaj A, Billert H, Dyderski S, Kasyna A, Zbrzeźna M. Influence of non-irradiated and UVA-irradiated l-arginine diprotoporphyrinate alone and in combination with 5-methoxypsoralen, on respiratory burst of human neutrophils in vitro. Curr Topics Biophys. 2004;28:9–14
  12. Łabędzka M, Gulyas H, Schmidt N, Gercken G. Toxicity of metallic ions and oxides to rabbit alveolar macrophages. Environ Res. 1989;48:255–274
  13. Allen RC. Phagocytic leukocyte oxygenation activities and chemiluminescence: a kinetic approach to analysis. Methods Enzymol. 1986;133:449–493
  14. Revision of criteria and protocols of assessment and classification of hazardous waste. The Environment agency R&D project no. P1-482. September 2002. (chapters C5.2 and C5.9.3).
  15. Bezdetnaya L, Zeghari N, Belitchenko I, et al. Spectroscopic and biological testing of photobleaching of porphyrins in solutions. Photochem Photobiol. 1996;64:382–386
  16. de Chatelet LR, Long GD, Shirley PS, et al. Mechanism of the luminol-dependent chemiluminescence of human neutrophils. J Immunol. 1982;129:1589–1593
  17. Morehouse KM, Sipe HJ, Mason RP. The one-electron oxidation of porphyrins pi-cation radicals by peroxidases: an electron spin resonance investigation. Arch Biochem Biophys. 1989;273:158–164
  18. Arnhold J. Properties, functions and secretion of human myeloperoxidase. Biochemistry (Moscow). 2004;1:4–9
  19. Wagner DK, Collins-Lech DK, Sohnle PG. Inhibition of neutrophil killing of Candida albicans by substances which quench hypochlorous acid and chloramines. Infect Immun. 1986;51:731–735
  20. El Benna J, Park J-W, Ruedi JM, Babior BM. Cell-free activation of the respiratory burst oxidase by protein kinase C.. Blood Cells Mol Dis. 1995;21:201–206
  21. Blackshear PJ. The MARCKS family of cellular protein kinase C substrates. J Biol Chem. 1993;268:1501–1504
  22. Wolff DJ, Naddelman RA, Lubeskie A, Saks DA. Inhibition of nitric oxide synthase isoforms by porphyrins. Arch Biochem Biophys. 1996;333:27–34
  23. van der Vliet A, Eiserich JP, Shigenaga MK, Cross CE. Reactive oxygen species and tyrosine nitration in the respiratory tract. Epiphenomena or a pathobiologic mechanism of disease?. Am J Respir Crit Care Med. 1999;160:1–9
  24. Seth P, Kumari R, Dikshit M, Srimai RC. Modulation of rat peripheral polymorphonuclear leukocyte response by nitric oxide and arginine, Blood; 84: p. 2741–8.
  25. Alderton WK, Cooper CG, Knowles RG. Nitric oxide synthases: structure, function and inhibition. Blood. 2001;357:593–615
  26. Wang JF, Komarov P, de Groot H. Luminol chemiluminescence in rat macrophages and granulocytes: the role of NO, O2/H2O2 and HOCl. Arch Biochem Biophys. 1993;304:189–196
  27. Waterfield JD, McGeer EG, McGeer PL. The peripheral benzodiazepine receptor ligand PK 11195 inhibits arthritis in the MRL-lpr mouse model. Rheumatology. 1999;38:1068–1073
  28. Rajtar G, Żółkowska D, Kleinrok Z. Effect of diazepam and clonazepam on the function of isolated rat platelet and neutrophil. Med Sci Monit. 2002;8:37–44
  29. Verma A, Snyder SH. Peripheral type benzodiazepine receptors. Ann Rev Pharmacol Toxicol. 1989;29:307–322
  30. Verma A, Snyder SH. Characterization of porphyrin interactions with peripheral type benzodiazepine receptors. Mol Pharmacol. 1988;34:800–805
  31. Kessel D, Antolovich M, Smith KM. The role of the pheripheral benzodiazepine receptor in the apoptotic response to photodynamic therapy. Photochem Photobiol. 2001;74:346–349
  32. Gilbert A, Bagott J. Essentials of molecular photochemistry. Oxford: Blackwell Scientific Publications; 1991;p. 91
  33. Hazan I, Dana R, Granot Y, Levy R. Cytosolic phospholipase A2 and its mode of activation in human neutrophils by opsonized zymosan. Correlation between 42/44kDa mitogen-activated protein kinase, cytosolic phospholipase A2 and NADPH oxidase. Biochem J. 1997;326:867–876
  34. Sergeant S, Mc Phail L. Opsonized zymosan stimulates the redistribution of protein kinase C isoforms in human neutrophils. J. Immunol. 1997;159:2877–2885
  35. Aviezer D, Cotton S, David M, et al. Porphyrin analogues as novel antagonists of fibroblasts growth factor and vascular endothelial growth factor receptor binding that inhibit endothelial cell proliferation, tumor progression and metastasis. Cancer Res. 2000;60:2973–2980
  36. Lee FY, Synergistic methods and compositions for treating cancer. 2003. US patent no. 6537988.

PII: S1572-1000(05)00157-2

doi: 10.1016/S1572-1000(05)00157-2

Photodiagnosis and Photodynamic Therapy
Volume 3, Issue 2 , Pages 106-111 , June 2006