Photodiagnosis and Photodynamic Therapy
Volume 3, Issue 2 , Pages 99-101, June 2006

Photodynamic therapy for Barrett's oesophagus: How I do it

  • J. Andrew C. Thorpe, FRCS, MB ChB

      Affiliations

    • Corresponding Author InformationTel.: +44 113 206 5404.
    • Yorkshire Laser Centre, UK
    • St James's University Hospital, First Floor, Lincoln Wing, Beckett Street, Leeds LS9 7TF, UK

published online 26 April 2006.

Summary 

Endoscopic photodynamic therapy (PDT) for Barrett's oesophagus with high-grade dysplasia or early carcinoma is undertaken after full investigation. Endoscopic assessment is mandatory to determine the extent of the Barrett's segment and neoplastic changes. Photofrin at 2mg/kgbw is used, followed 24–72h later by illumination of 630nm light, 200J/cm of lesion. The whole of the Barrett's segment should be exposed to illumination. Patients are followed up endoscopically at 3 months.

Keywords: Photodynamic therapy, Barrett's oesophagus

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PII: S1572-1000(06)00051-2

doi:10.1016/j.pdpdt.2006.03.002

Photodiagnosis and Photodynamic Therapy
Volume 3, Issue 2 , Pages 99-101, June 2006

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