Photodiagnosis and Photodynamic Therapy
Volume 3, Issue 2 , Pages 87-92 , June 2006

Bare fiber photodynamic therapy using porfimer sodium for esophageal disease

  • Herbert Wolfsen, MD

      Affiliations

    • Divisions of Gastroenterology and Hepatology, Mayo Clinic, 6A Davis Bldg., 4500 San Pablo Road, Jacksonville, FL 32224, USA
    • Divisions of Gastroenterology and Hepatology, Johns Hopkins University, Baltimore, MD, USA
    • Divisions of Gastroenterology and Hepatology, Ochsner Clinic, New Orleans, LA, USA
    • Divisions of Gastroenterology and Hepatology, University of Maryland, Baltimore, MD, USA
    • Divisions of Gastroenterology and Hepatology, Duke University, Durham, NC, USA
    • Divisions of Gastroenterology and Hepatology, Virginia Mason Medical Center, Seattle, WA, USA
    • Divisions of Gastroenterology and Hepatology, University of California, San Francisco, CA, USA
    • Divisions of Gastroenterology and Hepatology, University of Miami, Miami, FL, USA
    • Divisions of Gastroenterology and Hepatology, Mayo Clinic, Scottsdale, AZ, USA
    • Divisions of Gastroenterology and Hepatology, University of Pennsylvania, Philadelphia, PA, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1 904 953 2221; fax: +1 904 953 7260.
    • ,
  • Marcia Canto

      Affiliations

    • Divisions of Gastroenterology and Hepatology, Mayo Clinic, 6A Davis Bldg., 4500 San Pablo Road, Jacksonville, FL 32224, USA
    • Divisions of Gastroenterology and Hepatology, Johns Hopkins University, Baltimore, MD, USA
    • Divisions of Gastroenterology and Hepatology, Ochsner Clinic, New Orleans, LA, USA
    • Divisions of Gastroenterology and Hepatology, University of Maryland, Baltimore, MD, USA
    • Divisions of Gastroenterology and Hepatology, Duke University, Durham, NC, USA
    • Divisions of Gastroenterology and Hepatology, Virginia Mason Medical Center, Seattle, WA, USA
    • Divisions of Gastroenterology and Hepatology, University of California, San Francisco, CA, USA
    • Divisions of Gastroenterology and Hepatology, University of Miami, Miami, FL, USA
    • Divisions of Gastroenterology and Hepatology, Mayo Clinic, Scottsdale, AZ, USA
    • Divisions of Gastroenterology and Hepatology, University of Pennsylvania, Philadelphia, PA, USA
    • ,
  • Bob Etemad

      Affiliations

    • Divisions of Gastroenterology and Hepatology, Mayo Clinic, 6A Davis Bldg., 4500 San Pablo Road, Jacksonville, FL 32224, USA
    • Divisions of Gastroenterology and Hepatology, Johns Hopkins University, Baltimore, MD, USA
    • Divisions of Gastroenterology and Hepatology, Ochsner Clinic, New Orleans, LA, USA
    • Divisions of Gastroenterology and Hepatology, University of Maryland, Baltimore, MD, USA
    • Divisions of Gastroenterology and Hepatology, Duke University, Durham, NC, USA
    • Divisions of Gastroenterology and Hepatology, Virginia Mason Medical Center, Seattle, WA, USA
    • Divisions of Gastroenterology and Hepatology, University of California, San Francisco, CA, USA
    • Divisions of Gastroenterology and Hepatology, University of Miami, Miami, FL, USA
    • Divisions of Gastroenterology and Hepatology, Mayo Clinic, Scottsdale, AZ, USA
    • Divisions of Gastroenterology and Hepatology, University of Pennsylvania, Philadelphia, PA, USA
    • ,
  • Bruce Greenwald

      Affiliations

    • Divisions of Gastroenterology and Hepatology, University of Maryland, Baltimore, MD, USA
    • ,
  • Frank Gress

      Affiliations

    • Divisions of Gastroenterology and Hepatology, Mayo Clinic, 6A Davis Bldg., 4500 San Pablo Road, Jacksonville, FL 32224, USA
    • Divisions of Gastroenterology and Hepatology, Johns Hopkins University, Baltimore, MD, USA
    • Divisions of Gastroenterology and Hepatology, Ochsner Clinic, New Orleans, LA, USA
    • Divisions of Gastroenterology and Hepatology, University of Maryland, Baltimore, MD, USA
    • Divisions of Gastroenterology and Hepatology, Duke University, Durham, NC, USA
    • Divisions of Gastroenterology and Hepatology, Virginia Mason Medical Center, Seattle, WA, USA
    • Divisions of Gastroenterology and Hepatology, University of California, San Francisco, CA, USA
    • Divisions of Gastroenterology and Hepatology, University of Miami, Miami, FL, USA
    • Divisions of Gastroenterology and Hepatology, Mayo Clinic, Scottsdale, AZ, USA
    • Divisions of Gastroenterology and Hepatology, University of Pennsylvania, Philadelphia, PA, USA
    • ,
  • Drew Schembre

      Affiliations

    • Divisions of Gastroenterology and Hepatology, Mayo Clinic, 6A Davis Bldg., 4500 San Pablo Road, Jacksonville, FL 32224, USA
    • Divisions of Gastroenterology and Hepatology, Johns Hopkins University, Baltimore, MD, USA
    • Divisions of Gastroenterology and Hepatology, Ochsner Clinic, New Orleans, LA, USA
    • Divisions of Gastroenterology and Hepatology, University of Maryland, Baltimore, MD, USA
    • Divisions of Gastroenterology and Hepatology, Duke University, Durham, NC, USA
    • Divisions of Gastroenterology and Hepatology, Virginia Mason Medical Center, Seattle, WA, USA
    • Divisions of Gastroenterology and Hepatology, University of California, San Francisco, CA, USA
    • Divisions of Gastroenterology and Hepatology, University of Miami, Miami, FL, USA
    • Divisions of Gastroenterology and Hepatology, Mayo Clinic, Scottsdale, AZ, USA
    • Divisions of Gastroenterology and Hepatology, University of Pennsylvania, Philadelphia, PA, USA
    • ,
  • V. Raman Muthusamy

      Affiliations

    • Divisions of Gastroenterology and Hepatology, Mayo Clinic, 6A Davis Bldg., 4500 San Pablo Road, Jacksonville, FL 32224, USA
    • Divisions of Gastroenterology and Hepatology, Johns Hopkins University, Baltimore, MD, USA
    • Divisions of Gastroenterology and Hepatology, Ochsner Clinic, New Orleans, LA, USA
    • Divisions of Gastroenterology and Hepatology, University of Maryland, Baltimore, MD, USA
    • Divisions of Gastroenterology and Hepatology, Duke University, Durham, NC, USA
    • Divisions of Gastroenterology and Hepatology, Virginia Mason Medical Center, Seattle, WA, USA
    • Divisions of Gastroenterology and Hepatology, University of California, San Francisco, CA, USA
    • Divisions of Gastroenterology and Hepatology, University of Miami, Miami, FL, USA
    • Divisions of Gastroenterology and Hepatology, Mayo Clinic, Scottsdale, AZ, USA
    • Divisions of Gastroenterology and Hepatology, University of Pennsylvania, Philadelphia, PA, USA
    • ,
  • Afonso Ribeiro

      Affiliations

    • Divisions of Gastroenterology and Hepatology, Mayo Clinic, 6A Davis Bldg., 4500 San Pablo Road, Jacksonville, FL 32224, USA
    • Divisions of Gastroenterology and Hepatology, Johns Hopkins University, Baltimore, MD, USA
    • Divisions of Gastroenterology and Hepatology, Ochsner Clinic, New Orleans, LA, USA
    • Divisions of Gastroenterology and Hepatology, University of Maryland, Baltimore, MD, USA
    • Divisions of Gastroenterology and Hepatology, Duke University, Durham, NC, USA
    • Divisions of Gastroenterology and Hepatology, Virginia Mason Medical Center, Seattle, WA, USA
    • Divisions of Gastroenterology and Hepatology, University of California, San Francisco, CA, USA
    • Divisions of Gastroenterology and Hepatology, University of Miami, Miami, FL, USA
    • Divisions of Gastroenterology and Hepatology, Mayo Clinic, Scottsdale, AZ, USA
    • Divisions of Gastroenterology and Hepatology, University of Pennsylvania, Philadelphia, PA, USA
    • ,
  • Virender Sharma

      Affiliations

    • Divisions of Gastroenterology and Hepatology, Mayo Clinic, 6A Davis Bldg., 4500 San Pablo Road, Jacksonville, FL 32224, USA
    • Divisions of Gastroenterology and Hepatology, Johns Hopkins University, Baltimore, MD, USA
    • Divisions of Gastroenterology and Hepatology, Ochsner Clinic, New Orleans, LA, USA
    • Divisions of Gastroenterology and Hepatology, University of Maryland, Baltimore, MD, USA
    • Divisions of Gastroenterology and Hepatology, Duke University, Durham, NC, USA
    • Divisions of Gastroenterology and Hepatology, Virginia Mason Medical Center, Seattle, WA, USA
    • Divisions of Gastroenterology and Hepatology, University of California, San Francisco, CA, USA
    • Divisions of Gastroenterology and Hepatology, University of Miami, Miami, FL, USA
    • Divisions of Gastroenterology and Hepatology, Mayo Clinic, Scottsdale, AZ, USA
    • Divisions of Gastroenterology and Hepatology, University of Pennsylvania, Philadelphia, PA, USA
    • ,
  • Gregory Ginsberg

      Affiliations

    • Divisions of Gastroenterology and Hepatology, Mayo Clinic, 6A Davis Bldg., 4500 San Pablo Road, Jacksonville, FL 32224, USA
    • Divisions of Gastroenterology and Hepatology, Johns Hopkins University, Baltimore, MD, USA
    • Divisions of Gastroenterology and Hepatology, Ochsner Clinic, New Orleans, LA, USA
    • Divisions of Gastroenterology and Hepatology, University of Maryland, Baltimore, MD, USA
    • Divisions of Gastroenterology and Hepatology, Duke University, Durham, NC, USA
    • Divisions of Gastroenterology and Hepatology, Virginia Mason Medical Center, Seattle, WA, USA
    • Divisions of Gastroenterology and Hepatology, University of California, San Francisco, CA, USA
    • Divisions of Gastroenterology and Hepatology, University of Miami, Miami, FL, USA
    • Divisions of Gastroenterology and Hepatology, Mayo Clinic, Scottsdale, AZ, USA
    • Divisions of Gastroenterology and Hepatology, University of Pennsylvania, Philadelphia, PA, USA

References 

  1. Wolfsen HC. Present status of photodynamic therapy for high-grade dysplasia in Barrett's esophagus. J Clin Gastroenterol. 2005;39(3):189–202
  2. Wolfsen HC. Carpe luz-seize the light: endoprevention of esophageal adenocarcinoma when using photodynamic therapy with porfimer sodium. Gastrointest Endosc. 2005;62(4):499–503
  3. Overholt BF, Lightdale CJ, Wang KK, et al. Photodynamic therapy with porfimer sodium for ablation of high-grade dysplasia in Barrett's esophagus: international, partially blinded, randomized phase III trial. Gastrointest Endosc. 2005;62(4):488–498
  4. Laukka MA, Wang KK. Initial results using low-dose photodynamic therapy in the treatment of Barrett's esophagus. Gastrointest Endosc. 1995;42(1):59–63
  5. Prosst RL, Wolfsen HC, Gahlen J. Photodynamic therapy for esophageal diseases: a clinical update. Endoscopy. 2003;35(12):1059–1068
  6. Lovat LB, Jamieson NF, Novelli MR, et al. Photodynamic therapy with m-tetrahydroxyphenyl chlorin for high-grade dysplasia and early cancer in Barrett's columnar lined esophagus. Gastrointest Endosc. 2005;62(4):617–623
  7. Mlkvy P, Messmann H, Regula J, et al. Photodynamic therapy for gastrointestinal tumors using three photosensitizers—ALA induced PPIX, Photofrin and m-THPC. A pilot study. Neoplasma. 1998;45(3):157–161
  8. Sharma VK, Fleisher DE, Wang KK, Overholt B, Fennerty B. A randomized trial of radio-frequency ablation of specialized intestinal metaplasia of the esophagus. Gastrointest Endosc. 2004;59:AB113
  9. Panjehpour M, Overholt BF, Haydek JM. Light sources and delivery devices for photodynamic therapy in the gastrointestinal tract. Gastrointest Endosc Clin N Am. 2000;10(3):513–532
  10. Wang KK, Wongkeesong M, Buttar NS. American gastroenterological association technical review on the role of the gastroenterologist in the management of esophageal carcinoma. Gastroenterology. 2005;128(5):1471–1505
  11. Wallace MB, Perelman LT, Backman V, et al. Endoscopic detection of dysplasia in patients with Barrett's esophagus using light-scattering spectroscopy. Gastroenterology. 2000;119(3):677–682
  12. Noh KW, Raimondo M, Wallace MB, Wolfsen HC, Woodward TA. Fine needle aspiration of peritumoral lymph nodes in esophageal cancer with endobronchial ultrasound. Am J Gastroenterol. 2005;100:S262
  13. Noh KW, Woodward TA, Wallace MB. Emerging endoscopic techniques in oncology. Gastrointest Endosc Clin N Am. 2005;15(3):615–629x–xi
  14. Cameron AJ, Lomboy CT, Pera M, Carpenter HA. Adenocarcinoma of the esophagogastric junction and Barrett's esophagus. Gastroenterology. 1995;109(5):1541–1546
  15. Wang KK. Current Strategies in the management of Barrett's esophagus. Curr Gastroenterol Rep. 2005;7(3):196–201
  16. Dougherty TJ, Gomer CJ, Henderson BW, et al. Photodynamic therapy. J Natl Cancer Inst. 1998;90(12):889–905
  17. Georgakoudi I, Nichols MG, Foster TH. The mechanism of Photofrin photobleaching and its consequences for photodynamic dosimetry. Photochem Photobiol. 1997;65(1):135–144
  18. Sampliner RE. Endoscopic ablative therapy for Barrett's esophagus: current status. Gastrointest Endosc. 2004;59(1):66–69
  19. Overholt BF. Acid suppression and reepithelialization after ablation of Barrett's esophagus. Dig Dis. 2000;18(4):232–239
  20. Ukleja A, Scolapio JS, Wolfsen HC. Nutritional consequences following photodynamic therapy. Gastrotenterology. 1999;116(4, Part 2):A-582
  21. Ban S, Mino M, Nishioka NS, et al. Histopathologic aspects of photodynamic therapy for dysplasia and early adenocarcinoma arising in Barrett's esophagus. Am J Surg Pathol. 2004;28(11):1466–1473
  22. Hemminger LL, Wolfsen HC. Photodynamic therapy for Barrett's esophagus and high grade dysplasia: results of a patient satisfaction survey. Gastroenterol Nurs. 2002;25(4):139–141
  23. Wolfsen HC, Ng CS. Cutaneous consequences of photodynamic therapy. Cutis. 2002;69(2):140–142
  24. Wolfsen HC, Hemminger LL, Wallace MB, Devault KR. Clinical experience of patients undergoing photodynamic therapy for Barrett's dysplasia or cancer. Aliment Pharmacol Ther. 2004;20(10):1125–1131
  25. Wang KK, Nijhawan PK. Complications of photodynamic therapy in gastrointestinal disease. Gastrointest Endosc Clin N Am. 2000;10(3):487–495
  26. Panjehpour M, Overholt BF, Phan MN, Haydek JM. Optimization of light dosimetry for photodynamic therapy of Barrett's esophagus: efficacy vs. incidence of stricture after treatment. Gastrointest Endosc. 2005;61(1):13–18
  27. Sujendran V, Sica G, Warren B, Maynard N. Oesophagectomy remains the gold standard for treatment of high-grade dysplasia in Barrett's oesophagus. Eur J Cardiothorac Surg. 2005;28(5):763–766

PII: S1572-1000(06)00053-6

doi: 10.1016/j.pdpdt.2006.03.004

Photodiagnosis and Photodynamic Therapy
Volume 3, Issue 2 , Pages 87-92 , June 2006

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