Photodiagnosis and Photodynamic Therapy
Volume 3, Issue 3 , Pages 168-176 , September 2006

Autofluorescence and Photofrin-induced fluorescence imaging and spectroscopy in an animal model of oral cancer

  • Thomas Mang, PhD

      Affiliations

    • Department of Oral and Maxillofacial Surgery, University at Buffalo, School of Dental Medicine, Buffalo, NY, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1 716 829 3047; fax: +1 716 829 3019.
    • ,
  • James Kost

      Affiliations

    • Division of Biophysics and Bioimaging, Ontario Cancer Institute, Toronto, Canada
    • ,
  • Maureen Sullivan

      Affiliations

    • Roswell Park Cancer Institute, Department of Dentistry and Oral Prosthetics, Buffalo, NY, USA
    • ,
  • Brian C. Wilson

      Affiliations

    • Division of Biophysics and Bioimaging, Ontario Cancer Institute, Toronto, Canada
    • Department of Medical Biophysics, University of Toronto, Canada

References 

  1. Rodrigues VC, Moss SM, Tuomainen H. Oral cancer in the UK: to screen or not to screen. Oral Oncol. 1998;34(6):454–465
  2. Franceschi S, Barzan L, Talamini R. Screening for cancer of the head and neck: if not now, when?. Oral Oncol. 1997;33(5):313–316
  3. Oral cancer background papers: a working draft. In: National Strategic Planning Conference for the Prevention and Control of Oral and Pharyngeal Cancer, Chicago, 1996.
  4. Silverman S, Gorsky M, Lozada F. Oral leukoplakia and malignant transformation. A follow-up study of 257 patients. Cancer. 1984;53:563–568
  5. Lumerman H, Freedman P, Kerpel S. Oral epithelial dysplasia and the development of invasive squamous cell carcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endodontics. 1995;79(3):321–329
  6. Mashberg A, Samit AM. Early detection, diagnosis and management of oral and Oropharyngeal cancer. Cancer J Clin. 1989;39(2):67–88
  7. Mashberg A. Tolonium (toluidine blue) rinse—a screening method for recognition of squamous carcinoma. Continuing study of oral cancer IV. JAMA. 1981;245(23):2408–2410
  8. Mashberg A. Final evaluation of tolonium chloride rinse for screening of high-risk patients with asymptomatic squamous carcinoma. J Am Dental Assoc. 1983;106(3):319–323
  9. Mang TS, McGinnis C, Castillo N, Potter WR. Fluorescence detection of occult non-palpable metastases in lymph nodes following injection of low doses of Photofrin II. SPIE Proc Adv Photochem. 1988;997:118–125
  10. Mang TS, McGinnis C, Crean DH, Khan S, Liebow C. Fluorescence detection of tumors: studies on the early diagnosis of microscopic lesions in preclinical and clinical studies. J Cell Pharmacol. 1992;(3):132–140
  11. Crean DH, Liebow C, Penetrante RB, Mang TS. Evaluation of porfimer sodium fluorescence for measuring tissue transformation. Cancer. 1993;72(10):3068–3077
  12. Kolli VR, et al. Native cellular fluorescence of neoplastic upper aerodigestive mucosa. Arch Otolaryngol Head Neck Surg. 1995;121(11):1287–1292
  13. Kolli VR, et al. Native cellular fluorescence can identify changes in epithelial thickness in-vivo in the upper aerodigestive tract. Am J Surg. 1995;170(5):495–498
  14. Yang V, Yeow J, Lilge L, Kost J, Mang T, Wilson BC. Non-contact point spectroscopy guided by two-channel fluorescence imaging in a Hamster Cheek Pouch Model. SPIE Proc. 1999;3595:2–8
  15. Fuchs J, et al. Acute effects of near ultraviolet and visible light on the cutaneous antioxidant defense system. Photochem Photobiol. 1989;50(6):739–744
  16. DaCosta RS, Lilge L, Kost J. Confocal fluorescence microscopy, microspectrofluorimetry and modeling studies of laser induced fluorescence endoscopy (LIFE) of human colon tissue. SPIE Proc. 1996;2975:98–107
  17. DaCosta RS, Lilge L, Kost J. Confocal fluorescence microscopy/macroscopy and microspectrofluorimetry analysis of human colorectal tissues. J Anal Morphol Cell Vis. 1997;(4):24–29
  18. Yang VXD, Muller PJ, Herman P, Wilson BC. A multispectral fluorescence imaging system: design and initial clinical tests in intra-operative Photofrin-photodynamic therapy of brain tumors. Lasers Surg Med. 2003;32:224–232
  19. Gillenwater A, et al. Noninvasive diagnosis of oral neoplasia based on fluorescence spectroscopy and native tissue autofluorescence. Arch Otolaryngol Head Neck Surg. 1998;124(11):1251–1258

PII: S1572-1000(06)00063-9

doi: 10.1016/j.pdpdt.2006.04.003

Photodiagnosis and Photodynamic Therapy
Volume 3, Issue 3 , Pages 168-176 , September 2006

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