Photodiagnosis and Photodynamic Therapy
Volume 3, Issue 3 , Pages 162-167 , September 2006

Potential of cationic porphyrins for photodynamic treatment of cutaneous Leishmaniasis

  • Carrie-Anne Bristow

      Affiliations

    • Photobiology and Photomedicine Group, Department of Chemistry & Clinical Biosciences Institute, University of Hull, Kingston-upon-Hull HU6 7RX, United Kingdom
    • ,
  • Robert Hudson

      Affiliations

    • Photobiology and Photomedicine Group, Department of Chemistry & Clinical Biosciences Institute, University of Hull, Kingston-upon-Hull HU6 7RX, United Kingdom
    • ,
  • Timothy A. Paget, PhD

      Affiliations

    • Medway School of Pharmacy, The Universities of Kent and Greenwich at Medway, Kent ME4 4TB, United Kingdom
    • Corresponding Author InformationCorresponding author.
    • ,
  • Ross W. Boyle, PhD

      Affiliations

    • Photobiology and Photomedicine Group, Department of Chemistry & Clinical Biosciences Institute, University of Hull, Kingston-upon-Hull HU6 7RX, United Kingdom
    • Corresponding Author InformationCorresponding author. Tel.: +44 1482 466353; fax: +44 1482 466410.

References 

  1. The world health organisation website viewed 11/10/05 http://www.who.int/mediacentre/factsheets/fs116/en/.
  2. Desjeux P. Leishmaniasis—public health aspects and control. Clin Dermatol. 1996;14(5):417–423
  3. Herwaldt B. Leishmaniasis. The Lancet. 1999;354:1191–1199
  4. Henderson B, Dougherty T. How does photodynamic therapy work?. Photochem Photobiol. 1992;55(1):145–157
  5. MacDonald I, Dougherty T. Basic principles of photodynamic therapy. J Porphyrins Phthalocyanines. 2001;5:105–129
  6. Enk CD, Fritsch C, Jonas F, et al. Treatment of cutaneous leishmaniasis with photodynamic therapy. Arch Dermatol. 2003;139:432–434
  7. Gardlo K, Horska Z, Enk CD, et al. Treatment of cutaneous leishmaniasis by photodynamic therapy. J Am Acad Dermatol. 2003;48:893–896
  8. Sah JF, Ito H, Kolli BK, Peterson DA, Sassal S, Chang K-P. Genetic rescue of Leishmania deficiency in porphyrin biosynthesis creates mutants suitable for analysis of cellular events in uroporphyria and for photodynamic therapy. J Biol Chem. 2002;277:14902–14909
  9. Kassab K, Amor T, Jori G, Coppellotti O. Photosensitization of Colpdoda inflata cysts by meso-substituted cationic compounds. Photochem Photobiol Sci. 2002;1:560–564
  10. Kassab K, Dei D, Roncucci G, Jori G, Coppellotti O. Phthalocyanine-photosensitized inactivation of a pathogenic protozoan, Acanthamoeba palestinensis. Photochem Photobiol Sci. 2003;2:668–672
  11. Merchat M, Spikes J, Bertoloni G, Jori G. Studies on the mechanism of bacteria photosensitization by meso-substituted cationic compounds. J Photochem Photobiol B: Biol. 1996;35:149–157
  12. Segalla A, Boasarelli C, Braslavsky S, et al. Photophysical, photochemical and antibacterial photosensitizing properties of a novel octacationic Zn(II)-phthalocyanine. Photochem Photobiol Sci. 2002;1:641–648
  13. Hamblin M, O’Donnell D, Murthy N, Contag C, Hasan T. Rapid control of wound infections by targeted photodynamic therapy monitored by in vivo bioluminescence imaging. Photochem Photobiol. 2002;75:51–57
  14. Wainwright M. Photodynamic antimicrobial chemotherapy (PACT). J Antimicrob Chemother. 1998;42:13–28
  15. Hamblin M, Hasan T. Photodynamic therapy: a new antimicrobial approach to infectious disease?. Photochem Photobiol Sci. 2004;3:436–450
  16. Hudson R, Savoie H, Boyle RW. Lipophilic cationic compounds as photodynamic sensitisers, synthesis and structure-activity relationships. J Photodiagn Photodyn Therapy. 2005;2(3):193–196
  17. Obochi M, Boyle R, van Lier J. Biological activities of phthalocyanines. XIII. The effects of human serum components on the in vitro uptake of and photodynamic activity of zinc phthalocyanine. Photochem Photobiol. 1993;37:4
  18. Deyes R. Cell viability assays. Promega Notes. 2002;81:32–33
  19. Dutta S, Ray D, Kolli BK, Chang K-P. Photodynamic sensitisation of Leishmania amazonensis in both extracellular and intracellular stages with aluminium phthalocyanine chloride for photolysis in vitro. Antimicrob Agents Chemother. 2005;49:4474–4484

PII: S1572-1000(06)00064-0

doi: 10.1016/j.pdpdt.2006.04.004

Photodiagnosis and Photodynamic Therapy
Volume 3, Issue 3 , Pages 162-167 , September 2006

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