Photodiagnosis and Photodynamic Therapy
Volume 3, Issue 4 , Pages 214-226, December 2006

A clinical review of PDT for cutaneous malignancies

PDT Center, Leo Jenkins Cancer Institute, The Brody School of Medicine at ECU, Greenville, NC 27834, USA

published online 22 June 2006.

Summary 

More critical than for most other anatomy, intervention to cutaneous malignancy must not only be therapeutically successful but also achieve excellent cosmetic and functional outcome. As it can achieve those ends, PDT has moved to the forefront in the management of skin cancer. A number of well designed clinical trials and large patient series have reported outstanding outcomes for many histologies. This paper will review the rationale and outcomes of cutaneous PDT to malignancy using both topical and systemic photosensitizers. The benefits and drawbacks of cutaneous PDT are also examined.

Keywords: PDT, Cutaneous malignancy, Topical photosensitizers, Intravenous photosensitizers, Skin cancer

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PII: S1572-1000(06)00087-1

doi:10.1016/j.pdpdt.2006.05.002

Photodiagnosis and Photodynamic Therapy
Volume 3, Issue 4 , Pages 214-226, December 2006