Photodiagnosis and Photodynamic Therapy
Volume 4, Issue 3 , Pages 160-169 , September 2007

A comparison of susceptibility to photodynamic treatment between endothelial and tumor cells in vitro and in vivo

  • Ronald B. Moore, MD, PhD

      Affiliations

    • Corresponding Author InformationCorresponding author at: Department of Surgery and Oncology, University of Alberta, 2D2 Walter Mackenzie Health Sciences Centre, 8440-112 Street, Edmonton, Alberta, Canada T6G 2B7. Tel.: +1 780 407 6330; fax: +1 780 407 6331.
    • ,
  • Zhengwen Xiao
    • ,
  • John Tulip
    • ,
  • J.D. Chapman

References 

  1. Jocham D, Baumgartner R, Stepp H, Unsold E. Clinical experience with the integral photodynamic therapy of bladder carcinoma. J Photochem Photobiol B. 1990;6:183–187
  2. Nseyo UO, Shumaker B, Klein EA, Sutherland K  for the bladder Photofrin study group. Photodynamic therapy using porfimer sodium as an alternative to cystectomy in patients with refractory transitional cell carcinoma in situ of the bladder. J Urol. 1998;160:39–44
  3. Allison RR, Mota HC, Sibata CH. Clinical PD/PDT in North America: an historical review. Photodiagn Photodyn Ther. 2004;1:263–277
  4. Pandey RK, Bellnier DA, Smith KM, Doughtery TJ. Chlorine and porphyrin derivatives as potential photosensitizers and photodynamic therapy. Photochem Photobiol. 1991;53:65–72
  5. Foote CS. Mechanisms of photo-oxygenation. In:  Dorin DR,  Gomer CG editor. Porphyrin localization and treatment of tumors. New York: Alan R. Liss; 1984;p. 301–334
  6. Henderson BW, Miller AC. Effects of scavengers of reactive oxygen and radical species on cell survival following photodynamic treatment in vitro: comparison to ionizing radiation. Radiat Res. 1986;108:196–205
  7. Hilf R, Murant RS, Narayanan U, Gibson SL. Relationship of mitochondrial function and cellular adenosine triphosphate levels to hematoporphyrin derivatives-induced photosensitization in R-3230-AC mammary tumors. Cancer Res. 1986;46:211–217
  8. Henderson BW, Waldow SM, Mang TS, Potter WR, Malone PB, Dougherty TJ. Tumor destruction and kinetics of tumor cell death in two experimental mouse tumors following photodynamic therapy. Cancer Res. 1985;45:572
  9. Chan WS, Brasseur N, La Madeleine C, van Lier JE. Evidence for different mechanisms of EMT-6 tumor necrosis by photodynamic therapy with disulfonated aluminum phthalocyanine or Photofrin: tumor cell survival and blood flow. Anticancer Res. 1996;16(4A):1887–1892
  10. Moore RB, Chapman JD, Mercer JR, et al. Measurement of PDT-induced hypoxia in Dunning prostate tumors by iodine-123-iodoazomycin arabinoside. J Nucl Med. 1993;34:405–413
  11. Gilissen MJ, van de Merbel-de Wit LE, Star WM, Koster JF, Sluiter W. Effect of photodynamic therapy on the endothelium-dependent relaxation of isolated rat aortas. Cancer Res. 1993;53:2548–2552
  12. Berenbaum MC, Hall GW, Hoyes AD. Cerebral photosensitization by hematoporphyrin derivative: evidence for endothelial site of action. Br J Cancer. 1986;53:81–89
  13. Chaudhuri K, Keck RW, Selman SH. Morphological changes of tumor microvasculature following hematoporphyrin derivative sensitized photodynamic therapy. Photochem Photobiol. 1987;46:823–827
  14. Gomer CJ, Rucker N, Murphree AL. Differential cell photosensitivity following porphyrin photodynamic therapy. Cancer Res. 1988;48:4539–4542
  15. Castano AP, Demidova TN, Hamblin MR. Mechanism in photodynamic therapy: part one – photosensitizers, photochemistry and cellular localization. Photodiagn Photodyn Ther. 2004;1:279–293
  16. Chapman JD, McPhee MS, Walz N, et al. Nuclear magnetic resonance spectroscopy and sensitizer-adduct measurements of photodynamic therapy-induced ischemia in solid tumors. J Natl Cancer Inst. 1991;83:1650–1659
  17. Chapman JD, Stobbe CC, Arnfield MR, Santus R, Lee J, McPhee MS. Oxygen dependency of tumor cell killing in vitro by light-activated Photofrin II. Radiat Res. 1991;126:73–79
  18. Thorndyke C, Meeker BE, Thomas G, Lakey WH, McPhee MS, Chapman JD. The radiation sensitivities of R3327-H and R3327-AT rat prostatic adenocarcinomas. J Urol. 1985;134:191–198
  19. Vindelov LL, Christensen IJ, Nissen NI. Detergent-trypsin method for the preparation of nuclei for flowcytometric DNA analysis. Cytometry. 1983;3:323–327
  20. Tietze F. Enzymatic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues. Annual Biochem. 1969;27:502–522
  21. Boegheim JP, Scholte H, Dubbelman TM, Beems E, Raap A, van Steveninck J. Photodynamic effects of hematoporphyrin derivative on enzyme activities of murine L-929 fibroblasts. J Photochem Photobiol B. 1987;1:61–73
  22. Moore RB, Chapman JD, Mokrzanowski AD, Arnfield MR, McPhee MS, McEwan AJ. Non-invasive monitoring of photodynamic therapy with 99technetium HMPAO scintigraphy. Br J Cancer. 1992;65:491–497
  23. Xiao Z, Tamimi Y, Brown K, Tulip J, Moore R. Interstitial photodynamic therapy in subcutaneously implanted urologic tumors in rats after intravenous administration of 5-aminolevulinic acid. Urologic Oncol. 2002;7:125–132
  24. West CML, West DC, Kumar S, Moore JV. A comparison of the sensitivity to photodynamic treatment of endothelial and tumor cells in different proliferative states. Int J Radiat Biol. 1990;58:145–156
  25. Moan J, Sommer S. Oxygen dependence of photosensitizing effect of hematoporphyrin derivative in NHIK-3025 cells. Cancer Res. 1985;45:1608–1610
  26. Henderson BW, Fingar VH. Relationship of tumor hypoxia and response to photodynamic treatment in an experimental mouse tumor. Cancer Res. 1987;47:3110–3114
  27. Tseng MT, Reed MWR, Ackermann DM, Schuschke DA, Wieman TJ, Miller FN. Photodynamic therapy induced ultrastructural alterations in microvasculature of the rat cremaster muscle. Photochem Photobiol. 1988;48:675–681
  28. Ali SM, Olivo M, Yuen GY, Chee SK. Photodynamic-induced apoptosis of human nasopharyngeal carcinoma cells using Hypocrellins. Intl J Oncol. 2001;19:633–643
  29. Castano AP, Demidova TN, Hamblin MR. Mechanism in photodynamic therapy: part two-cellular signaling, cell metabolism and modes of cell death. Photodiagn Photodyn Ther. 2005;2:1–23
  30. Heiskanen KM, Bhat MB, Wang HW, Ma J, Nieminen A. Mitochondrial depolarization accompanies cytochrome c release during apoptosis in PC 6 Cells. J Biol Chem. 1999;274(9):5654–5658
  31. Aoki M, Nata T, Morishita R, et al. Endothelial apoptosis induced by oxidative stress through activation of NF-kB: antiapoptotic effect of antioxidant agents on endothelial cells. Hypertension. 2001;38:48–55
  32. Foster TH, Primavera MC, Marder VJ, Hilf R, Sporn LA. Photosensitized release of von Willebrand factor from cultured human endothelial Cell. Cancer Res. 1991;51:3261–3266
  33. Fingar VH, Wieman TJ, Doak KW. Mechanistic studies of PDT-induced vascular damage: evidence that eicosanoids mediate this process. Int J Radiat Biol. 1991;60:303–309
  34. Fingar VH, Wieman TJ, Wiehle SA, Cerrito PB. The role of microvascular damage in photodynamic therapy: the effect of treatment on vessel constriction, permeability and leukocyte adhesion. Cancer Res. 1992;52(18):4914–4921
  35. Reilly MP, Delanty N, Ray L, et al. Increased formation of the isoprostanes IPF2α-I and 8-epi-prostaglandin F2α in acute coronary angioplasty: evidence for oxidant stress during coronary reperfusion in humans. Circulation. 1997;96:3314–3320
  36. Fingar VH, Wieman TJ, Doak KW. Role of Thromboxane and prostacyclin release on photodynamic therapy-induced tumor destruction. Cancer Res. 1990;50:2599–2603
  37. Fingar VH, Kik PK, Cerrito PB, Tseng M, Abang E, Wieman TJ. Analysis of acute vascular damage after photodynamic therapy using benzoporphyrin derivative (BPD). Br J Cancer. 1999;79:1702–1708
  38. Korbelik M, Krosl G, Olive PL, Chaplin DJ. Distribution of Photofrin between tumor cells and tumor associated macrophages. Br J Cancer. 1991;64(3):508–512
  39. Korbelik M, Krosl G. Cellular levels of photosensitizers in tumors: the role of proximity to the blood supply. Br J Cancer. 1994;70(4):604–612
  40. Korbelik M, Sun J, Zeng H. Ischemia-reperfusion injury in photodynamic therapy-treated mouse tumors. Br J Cancer. 2003;88(5):760–766
  41. Xiao Z, Brown K, Tulip J, Moore RB. Whole bladder photodynamic therapy of orthotopic superficial bladder cancer in rats: a study of intravenous and intravesical administration of photosensitizers. J Urol. 2003;169(1):352–356
  42. Nathan TR, Whitelaw BE, Chang SC, et al. Photodynamic therapy for prostate cancer recurrence after radiotherapy: a phase I study. J Urol. 2002;168:1427–1432
  43. Weersink RA, Bogaards A, Gertner M, et al. Techniques for delivery and monitoring of TOOKAD (WST09)-mediated photodynamic therapy of the prostate: clinical experience and practicalities. J Photochem Photobiol B. 2005;79(3):211–222

PII: S1572-1000(07)00003-8

doi: 10.1016/j.pdpdt.2006.12.003

Photodiagnosis and Photodynamic Therapy
Volume 4, Issue 3 , Pages 160-169 , September 2007

Article Tools

* Image Usage & Resolution