Photodiagnosis and Photodynamic Therapy
Volume 4, Issue 2 , Pages 95-99 , June 2007

Microvascular effects of Photofrin®-induced photodynamic therapy

  • Cheng-Jen Chang, MD, PhD

      Affiliations

    • School of Medicine, Chang Gung University, and Department of Plastic Surgery, Chang Gung Memorial Hospital, 199, Tung Hwa North Road, Taipei, Taiwan
    • Corresponding Author InformationCorresponding author. Tel.: +886 2 27135211x3502; fax: +886 2 25140600.
    • ,
  • Sally M.H. Cheng

      Affiliations

    • School of Medicine, University of Melbourne, Melbourne, Australia
    • ,
  • J. Stuart Nelson

      Affiliations

    • Beckman Laser Institute and Medical Clinic, University of California, Irvine, CA, USA

References 

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  2. Bowers RE, Graham EA, Omlinson KM. The natural history of the strawberry nevus. Arch Dermatol. 1960;82:667–680
  3. Mulliken JB, Glowacki J. Hemangiomas and vascular malformations in infants and children: a classification based on endothelial characteristics. Plast Reconstr Surg. 1982;69:412–420
  4. Burton-Esterly N. Cutaneous hemangiomas, vascular stains, and associated syndromes. Current problems in pediatrics. Chicago: Yearbook Medical Publishers; 1987;p. 1–69
  5. In:  Ryan TJ,  Cherry GW editor. Vascular birthmarks: pathogenesis and management. Oxford: Oxford University Press; 1987;p. 75–79
  6. In:  Mulliken JB,  Young AE editor. Vascular birthmarks, hemangiomas, and malformations. Philadelphia: Saunders; 1988;p. 51–6186–102
  7. Spikes JD. The historical development of ideas on applications of photosensitized reactions in the health sciences. In:  Benasson RV,  Jori G,  Land EJ,  Truscott TG editor. Primary photo-processes in biology and medicine. NY: Plenum Press; 1985;p. 209–227
  8. Foote CS. Photosensitized oxidation and singlet oxygen: consequences in biological systems. In:  Pryor WA editors. Radicals in biology. vol. 2:NY: Academic Press; 1976;p. 85–102
  9. Chang CJ, Sun CH, Liaw LHL, Nelson JS, Berns MW. In vitro and in vivo photosensitizing capabilities of 5-ALA compared to Photofrin® in vascular endothelial cells. Lasers Surg Med. 1999;24:178–186
  10. Knighton D, Ausprunk D, Tapper D, Folkman J. Avascular and vascular phases of tumor growth in the chick embryo. Br J Cancer. 1977;35:347–356
  11. Kimel S, Svaasand LO, Hammer-Wilson M, et al. Demonstration of synergistic effects of hyperthermia and photodynamic therapy using the chick chorioallantoic membrane model. Lasers Surg Med. 1992;12:432–440
  12. DeFouw D, Rizzo VJ, Parrish RN. Mapping of the microcirculation in the chick chorioallantoic membrane during normal angiogenesis. Microvasc Res. 1989;38:136–137
  13. Chang CJ, Yang JY, Weng CJ, Wei FC. Pilot in vitro toxicity study of 5-ALA and Photofrin® in microvascular endothelial cells cultures. J Clin Laser Med Surg. 1997;15:83–87
  14. Chang CJ, Ma SF, Wei FC. Photosensitizing capabilities of Photofrin® in vascular endothelial cells. Formosa J Surg. 2001;34(6):287–293
  15. Weishaupt KR, Gomer CJ, Dougherty TJ. Identification of singlet oxygen as the cytotoxic agent in photoinactivation of a murine tumor. Cancer Res. 1976;36:2326–2329
  16. Berns MW, Coffey J, Wile AG. Laser photoradiation therapy of cancer: possible role of hyperthermia. Lasers Surg Med. 1984;4:87–92
  17. Nelson JS, Liaw L-H, Berns MW. Mechanism of tumor destruction in photodynamic therapy. Photochem Photobiol. 1987;46:829–836
  18. Nelson JS, Liaw L-H, Orenstein A, Robert WG, Berns MW. Mechanism of tumor destruction following photodynamic therapy with hematoporphyrin derivative, chlorine and phthalocyanine. JNCI. 1988;80:1599–1605
  19. Homer DW, Lemeshaw S. Applied logistic regression. New York: John Wiley; 1989;
  20. Berns MW, Hammer-Wilson M, Walter RJ, et al. Uptake and localization of HpD and active fraction in tissue culture and in serially biopsy human tumors. Adv Exp Med Biol. 1983;170:501–520
  21. Gaullier JM, Geze M, Santus R, et al. Subcellular localization of and photosensitization by protoporphyrin IX in human keratinocytes and fibroblasts cultivated with 5-aminolevulinic acid. Photochem Photobiol. 1995;62:114–122
  22. Gibson SL, Hilf R. Interdependence of fluence, drug dose and oxygen on hematoporphyrin derivative induced photosensitization of tumor mitochondria. Photochem Photobiol. 1985;42:367–373
  23. Gullino PM, Grantham FH. The influence of the host and the neoplastic cell population on the collagen content of a tumor mass. Cancer Res. 1963;23:648–653

PII: S1572-1000(07)00036-1

doi: 10.1016/j.pdpdt.2007.03.003

Photodiagnosis and Photodynamic Therapy
Volume 4, Issue 2 , Pages 95-99 , June 2007

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