Photodiagnosis and Photodynamic Therapy
Volume 5, Issue 1 , Pages 50-57 , March 2008

Comparison of photodynamic therapy and pulsed dye laser in patients with port wine stain birthmarks: A retrospective analysis

  • Kai-Hua Yuan, MD

      Affiliations

    • Laser Plastic and Aesthetic Center, PLA General Hospital of Guangzhou District, Guangzhou, PR China
    • Corresponding Author InformationCorresponding author at: Laser Plastic and Aesthetic Center, PLA General Hospital of Guangzhou District, No. 111, Liuhua Road, Guangzhou 510010, PR China.
    • ,
  • Qin Li

      Affiliations

    • Laser Plastic and Aesthetic Center, PLA General Hospital of Guangzhou District, Guangzhou, PR China
    • ,
  • Wen-Lin Yu

      Affiliations

    • Laser Plastic and Aesthetic Center, PLA General Hospital of Guangzhou District, Guangzhou, PR China
    • ,
  • Dong Zeng

      Affiliations

    • Laser Plastic and Aesthetic Center, PLA General Hospital of Guangzhou District, Guangzhou, PR China
    • ,
  • Chao Zhang

      Affiliations

    • Department of Medical Statistics, South China Medical University, Guangzhou, PR China
    • ,
  • Zheng Huang

      Affiliations

    • Department of Radiation Oncology, University of Colorado, Denver, CO 80045, USA

References 

  1. Kelly KM, Choi B, McFarlane S, et al. Description and analysis of treatments for port-wine stain birthmarks. Arch Facial Plast Surg. 2005;7:287–294
  2. Alster TS, Railan D. Laser treatment of vascular birthmarks. J Craniofac Surg. 2006;17:720–723
  3. Liu CL, Yuan KH, Zhang YZ, Fu Q, Yuan WW. Clinical study of double-frequency Nd:YAG 532nm laser for the treatment of skin vascular lesions. J Pract Aesthet Plast Surg. 1998;9:230–234[in Chinese]
  4. Anderson RR, Parrish JA. Selective photothermolysis: precise microsurgery by selective absorption of pulsed radiation. Science. 1983;220:524–527
  5. Schmults CD. Laser treatment of vascular lesions. Dermatol Clin. 2005;23:745–755
  6. Chen B, Pogue BW, Hoopes PJ, Hasan T. Vascular and cellular targeting for photodynamic therapy. Crit Rev Eukaryot Gene Expr. 2006;16:279–305
  7. Schmidt-Erfurth U, Hasan T. Mechanisms of action of photodynamic therapy with verteporfin for the treatment of age-related macular degeneration. Surv Ophthalmol. 2000;45:195–214
  8. Huang Z. A review of progress in clinical photodynamic therapy. Technol Cancer Res Treat. 2005;4:283–294
  9. Huang Z. Photodynamic therapy in China: 25 years of unique history. Part II. Clinical experience. Photodiag Photodyn Ther. 2006;3:71–84
  10. Loffeld A, Zaki I, Abdullah A, Lanigan S. Study of patient-reported morbidity following V-beam pulsed-dye laser treatment of port wine stains. Lasers Med Sci. 2005;20:114–116
  11. Kono T, Groff WF, Sakurai H. Treatment of port wine stains with the pulse dye laser. Ann Plast Surg. 2006;56:460–463
  12. Jasim ZF, Handley JM. Treatment of pulsed dye laser-resistant port wine stain birthmarks. J Am Acad Dermatol. 2007;57:677–682
  13. Qin ZP, Li KL, Ren L, Liu XJ. Photodynamic therapy of port wine stains–a report of 238 cases. Photodiag Photodyn Ther. 2007;4:53–59
  14. Lanigan SW. Improving the treatment of port wine stain birthmarks. Photodiag Photodyn Ther. 2007;4:143–144
  15. Lin XX, Wang W, WU. SF, Yang C, Chang TS. Treatment of capillary vascular malformation (port-wine stains) with photochemotherapy. Plast Reconstr Surg. 1997;99:1826–1830
  16. Waner M, Suen JY. A classification of congenital vascular lesions. In:  Waner M,  Suen JY editor. Hemangiomas and vascular malformations of the head and neck.. New York: Wiley-Liss; 1999;p. 1–12
  17. Chapas AM, Eickhorst K, Geronemus RG. Efficacy of early treatment of facial port wine stains in newborns: a review of 49 cases. Lasers Surg Med. 2007;39:563–568
  18. Kelly KM, Nelson JS. Update on the clinical management of port wine stains. Lasers Med Sci. 2000;15:220–226
  19. Wang H, Wang J, Jin H, Wen S, Jiang G. Flashlamp-pumped pulsed dye laser in treatment of port-wine stains. Chin Med Sci J. 2001;16:56–58
  20. Sharma VK, Khandpur S. Efficacy of pulsed dye laser in facial port-wine stains in Indian patients. Dermatol Surg. 2007;33:560–566
  21. Greve B, Raulin C. Prospective study of port wine stain treatment with dye laser: comparison of two wavelengths (585nm vs. 595nm) and two pulse durations (0. 5 milliseconds vs. 20 milliseconds). Lasers Surg Med. 2004;34:168–173
  22. Seukeran DC, Collins P, Sheehan-Dare RA. Adverse reactions following pulsed tunable dye laser treatment of port wine stains in 701 patients. Br J Dermatol. 1997;136:725–729
  23. Willey A, Anderson RR, Azpiazu JL, et al. Complications of laser dermatologic surgery. Lasers Surg Med. 2006;38:1–15
  24. Huang NY. What is the optimal PDT protocol for treating port wine stains (PWS)?. Photodiag Photodyn Ther. 2007;4:145–146
  25. Michel S, Landthaler M, Hohenleutner U. Recurrence of port-wine stains after treatment with the flashlamp-pumped pulsed dye laser. Br J Dermatol. 2000;143:1230–1234
  26. Soueid A, Waters R. Re-emergence of port wine stains following treatment with flashlamp-pumped dye laser 585nm. Ann Plast Surg. 2006;57:260–263
  27. Huikeshoven M, Koster PH, de Borgie CA, Beek JF, van Gemert MJ, van der Horst CM. Redarkening of port-wine stains 10 years after pulsed-dye-laser treatment. N Engl J Med. 2007;356:1235–1240
  28. Nelson JS, Geronemus RG. Redarkening of port-wine stains 10 years after laser treatment. N Engl J Med. 2007;356:2745–2746
  29. Jiang L, Gu Y, Li X, et al. Changes of skin perfusion after photodynamic therapy for port wine stain. Chin Med J (Engl). 1998;111:136–138
  30. Huang Z. Photodynamic therapy in China: 25 years of unique history. Part 1. History and domestic photosensitizers. Photodiag Photodyn Ther. 2006;3:3–10
  31. Yuan KH, Huang Z. Evolving role of PDT in PWS. Photodiag Photodyn Ther. 2007;4:149–150
  32. Xu DY, Chen WH, Zhang H, Shen NC. Study on a new drug for photodynamic therapy—hematoporphyrin monomethyl ether. Chin J Laser Med Surg. 1993;2:1–5[in Chinese]
  33. Kelly KM. Current treatment options for port wine stain birthmarks. Photodiag Photodyn Ther. 2007;4:147–148
  34. Kelly KM, Kimel S, Smith T, et al. Combined photodynamic and photothermal induced injury enhances damage to in vivo model blood vessels. Lasers Surg Med. 2004;34:407–413
  35. Yuan KH, Li Q, Yu WL, Xia LJ, Wang WL, Cai JH. A clinical analysis of treating port wine stains by combining photodynamic therapy with pulsed dye laser. Appl Laser. 2006;26(465/466):472;[in Chinese]

PII: S1572-1000(07)00127-5

doi: 10.1016/j.pdpdt.2007.12.001

Photodiagnosis and Photodynamic Therapy
Volume 5, Issue 1 , Pages 50-57 , March 2008

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