Photodiagnosis and Photodynamic Therapy
Volume 5, Issue 3 , Pages 224-227, September 2008

Adeno-carcinoma of the pharyngo-oesophageal junction and cervical oesophagus in a patient with an oesophagus lined entirely by columnar epithelium:

Report of a case treated by photodynamic therapy (PDT)

  • K. Moghissi, BSc, MD, FRCS (ED & Eng), FETCS

      Affiliations

    • The Yorkshire Laser Centre, Goole & District Hospital, Woodland Avenue, Goole, UK
    • Corresponding Author InformationCorresponding author. Tel.: +44 1724 290456.
  • ,
  • Kate Dixon

      Affiliations

    • The Yorkshire Laser Centre, Goole & District Hospital, Woodland Avenue, Goole, UK
  • ,
  • Anne Campbell

      Affiliations

    • The Yorkshire Laser Centre, Goole & District Hospital, Woodland Avenue, Goole, UK
    • Department of Histopathology, Hull & East Yorkshire Hospitals NHS Trust, UK

published online 03 November 2008.

Summary 

A case of adenocarcinoma in the pharyngo oesophageal junction extending to the upper cervical oesophagus is described. In this case the neo-plastic changes had occurred from columnar epithelium of gastric and intestinal type: Barrett’s oesophagus. The Barrett’s mucosa involved the whole length of the oesophagus. Because of the general condition of the patient and advanced stage of the tumour surgical treatment was considered inappropriate. Endoscopic Photofrin Photodynamic Therapy was used with good palliation of dysphagia. The patient survived for 9 months, dying form carcinomatosis and oesophago-airway fistula. As far as can be documented only one such case has been previously reported in the literature.

Keywords: Cervical adenocarcinoma of the oesophagus, Barrett’s oesophagus, PDT, Photodynamic therapy

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PII: S1572-1000(08)00083-5

doi:10.1016/j.pdpdt.2008.10.002

Photodiagnosis and Photodynamic Therapy
Volume 5, Issue 3 , Pages 224-227, September 2008