Photodiagnosis and Photodynamic Therapy
Volume 5, Issue 4 , Pages 260-263, December 2008

Fluorescence image-guided surgery of brain tumors: Explained step-by-step

  • M. Sam Eljamel, MD, FRCSEd&Ir, FRCS(SN)

      Affiliations

    • Corresponding Author InformationTel.: +44 1382 425712; fax: +44 1382 496202.

Department of Neurosurgery, Ninewells Hospital and Medical School, Dundee, DD1 9SY Scotland, UK

Received 20 November 2008; accepted 25 November 2008. published online 09 February 2009.

Summary 

Fluorescence image-guided surgery (FIGS) and fluorescence-guided resection (FGR) are surgical techniques used to maximise tumor excision and minimise collateral damage. FIGS and FGR combine preoperative photosensitizer-administration and fluorescence detection during surgery, by illumination of the surgical field using the appropriate wavelength and observing the fluorescence via a long-pass filter that allows fluorescent tumor to be seen by the surgeon. Commercially available technology has led to gross total resection of enhancing brain tumors in 65% of patients compared to merely 35% under standard white light surgery. This is a step-by-step synopsis of the techniques of FIGS in brain.

Keywords: ALA, Brain, Fluorescence, Photodiagnosis, PDT

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PII: S1572-1000(08)00108-7

doi:10.1016/j.pdpdt.2008.11.003

Photodiagnosis and Photodynamic Therapy
Volume 5, Issue 4 , Pages 260-263, December 2008

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