Photodiagnosis and Photodynamic Therapy
Volume 5, Issue 4 , Pages 251-255 , December 2008

Aminolevulinic acid (ALA)-assisted photodynamic diagnosis of subclinical and latent HPV infection of external genital region

  • Hong-Wei Wang, MD

      Affiliations

    • Shanghai Skin Diseases and STD Hospital, Shanghai 200050, China
    • Corresponding Author InformationCorresponding author.
    • ,
  • Xiu-Li Wang

      Affiliations

    • Shanghai Skin Diseases and STD Hospital, Shanghai 200050, China
    • ,
  • Ling-Lin Zhang

      Affiliations

    • Shanghai Skin Diseases and STD Hospital, Shanghai 200050, China
    • ,
  • Ming-Xia Guo

      Affiliations

    • Shanghai Skin Diseases and STD Hospital, Shanghai 200050, China
    • ,
  • Zheng Huang

      Affiliations

    • University of Colorado Denver, Aurora 80045, USA

References 

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  2. Wikstrom A, Hedblad MA, Johansson B, et al. The acetic acid test in evaluation of subclinical genital papillomavirus infection: a comparative study on penoscopy, histopathology, virology and scanning electron microscopy findings. Sex Transm Inf. 1992;68:90–99
  3. Schneede P, Munch P, Wagner S, et al. Fluorescence urethroscopy following instillation of 5-aminolevulinic acid: a new procedure for detecting clinical and subclinical HPV lesions of the urethra. J Eur Acad Dermatol Venereol. 2000;15:121–125
  4. Fehr MK, Chapman CF, Krasieva T, et al. Selective photosensitizer distribution in vulvar condyloma acuminatum after topical application of 5-aminolevulinic acid. Am J Obstet Gynecol. 1996;174:951–957
  5. Fehr MK, Hornung R, Degen A, et al. Photodynamic therapy of vulvar and vaginal condyloma and intraepithelial neoplasia using topically applied 5-aminolevulinic acid. Lasers Surg Med. 2002;30:273–279
  6. Frank GB, Bos JD. Photodynamic therapy for condylomata acuminata with local application of 5-aminolevulinic acid. Sex Transm Inf. 1996;72:70–71
  7. Ross EV, Romero R, Kollias N, Crum C, Anderson RR. Selectivity of protoporphyrin IX fluorescence for condylomata after topical application of 5-aminolaevulinic acid: implications for photodynamic treatment. Br J Dermatol. 1997;137:736–742
  8. Wang XL, Wang HW, Wang HS, et al. Topical 5-aminolevulinic acid-photodynamic therapy for the treatment of urethral condylomata acuminata. Br J Dermatol. 2004;151:880–885
  9. Wang XL, Wang HW, Huang Z, et al. Study of protoporphyrin IX (PpIX) pharmacokinetics after topical application of ALA in urethral condylomata acuminata. Photochem Photobiol. 2007;83:1–5
  10. Anorlu RI. What is the significance of the HPV epidemic?. Can J Urol. 2008;15:3860–3865
  11. Dempsey AF, Koutsky LA. National burden of genital warts: a first step in defining the problem. Sex Transm Dis. 2008;35:361–362
  12. Chow LT, Broker TR. Mechanisms and regulation of papillomavirus DNA replication. In:  Saveria Campo M editors. Papillomavirus research: from natural history to vaccines and beyond. Caister Academic Press; 2006;p. 193–206
  13. Wu TT, Qu JY. Assessment of the relative contribution of cellular components to the acetowhitening effect in cell cultures and suspensions using elastic light-scattering spectroscopy. Appl Opt. 2007;46:4834–4842
  14. Ferenczy A, Behelak Y, Haber G, Wright TC, Richart RM. Treating vaginal and external anogenital condylomas with electrosurgery vs CO2 laser ablation. J Gynecol Surg. 1995;11:41–50
  15. Stefanaki IM, Georgiou S, Themelis GC, Vazgiouraki EM, Tosca AD. In vivo fluorescence kinetics and photodynamic therapy in condylomata acuminata. Br J Dermatol. 2003;149:972–976
  16. Krammer B, Plaetzer K. ALA and its clinical impact, from bench to bedside. Photochem Photobiol Sci. 2008;7:283–289
  17. Lesar A, Padgett M, O’Dwyer M, Ferguson J, Moseley H. Fluorescence induced by aminolevulinic acid and methyl aminolevulinate on normal skin. Photodiagn Photodyn Ther. 2007;4:224–229

PII: S1572-1000(08)00109-9

doi: 10.1016/j.pdpdt.2008.11.004

Photodiagnosis and Photodynamic Therapy
Volume 5, Issue 4 , Pages 251-255 , December 2008

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