Photodiagnosis and Photodynamic Therapy
Volume 7, Issue 2 , Pages 134-136 , June 2010

Can surgical site infections be treated by photodynamic therapy?

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  2. Ragas X, Dai T, Tegos GP, Agut M, Nonell S, Hamblin MR. Photodynamic inactivation of Acinetobacter baumannii using phenothiazinium dyes: in vitro and in vivo studies. Laser Surg Med, in press.
  3. Demidova TN, Hamblin MR. Effect of cell-photosensitizer binding and cell density on microbial photoinactivation. Antimicrob Agents Chemother. 2005;49:2329–2335
  4. Gad F, Zahra T, Francis KP, Hasan T, Hamblin MR. Targeted photodynamic therapy of established soft-tissue infections in mice. Photochem Photobiol Sci. 2004;3:451–458
  5. Biel MA. Photodynamic therapy utilizing a solution of photosensitizing compound and surfactant. US Patent 7229447 (2007).
  6. Bugaj A, Juzeniene A, Juzenas P, Iani V, Ma LW, Moan J. The effect of skin permeation enhancers on the formation of porphyrins in mouse skin during topical application of the methyl ester of 5-aminolevulinic acid. J Photochem Photobiol B. 2006;83:94–97
  7. Donnelly RF, Morrow DI, McCarron PA, David Woolfson A, Morrissey A, Juzenas P, et al. Microneedle arrays permit enhanced intradermal delivery of a preformed photosensitizer. Photochem Photobiol. 2009;85:195–204
  8. Taberner AJ, Ball NB, Hogan NC, Hunter IW. A portable needle-free jet injector based on a custom high power-density voice-coil actuator. Conf Proc IEEE Eng Med Biol Soc. 2006;1:5001–5004
  9. Gelfuso GM, Figueiredo FV, Gratieri T, Lopez RF. The effects of pH and ionic strength on topical delivery of a negatively charged porphyrin (TPPS4). J Pharm Sci. 2008;97:4249–4257
  10. Haedersdal M, Sakamoto FH, Farinelli WA, Doukas AG, Tam J, Anderson RR. Fractional CO(2) laser-assisted drug delivery. Lasers Surg Med. 2010;42:113–122
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  12. Hamblin MR, O’Donnell DA, Murthy N, Rajagopalan K, Michaud N, Sherwood ME, et al. Polycationic photosensitizer conjugates: effects of chain length and Gram classification on the photodynamic inactivation of bacteria. J Antimicrob Chemother. 2002;49:941–951
  13. Tegos GP, Anbe M, Yang C, Demidova TN, Satti M, Mroz P, et al. Protease-stable polycationic photosensitizer conjugates between polyethyleneimine and chlorin(e6) for broad-spectrum antimicrobial photoinactivation. Antimicrob Agents Chemother. 2006;50:1402–1410
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  16. Azarpazhooh A, Shah PS, Tenenbaum HC, Goldberg MB. The effect of photodynamic therapy for periodontitis: a systematic review and meta-analysis. J Periodontol. 2010;81:4–14
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  19. Tegos GP, Masago K, Aziz F, Higginbotham A, Stermitz FR, Hamblin MR. Inhibitors of bacterial multidrug efflux pumps potentiate antimicrobial photoinactivation. Antimicrob Agents Chemother. 2008;52:3202–3209
  20. Tegos GP, Hamblin MR. Phenothiazinium antimicrobial photosensitizers are substrates of bacterial multidrug resistance pumps. Antimicrob Agents Chemother. 2006;50:196–203
  21. Brown SB. Clinical developments in antimicrobial PDT. In: 12th international photodynamic association world congress, Seattle, 2009.

PII: S1572-1000(10)00050-5

doi: 10.1016/j.pdpdt.2010.04.004

Photodiagnosis and Photodynamic Therapy
Volume 7, Issue 2 , Pages 134-136 , June 2010

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