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Hyaluronic acid-functionalized mesoporous silica nanoparticles for efficient photodynamic therapy of cancer cells
01 February 2012
Magali Gary-Bobo, David Brevet, Nadia Benkirane-Jessel, Laurence Raehm, Philippe Maillard, Marcel Garcia, Jean-Olivier Durand
Summary: Mesoporous silica nanoparticles (MSN) for photodynamic therapy (PDT) were coated with poly-(l-lysine) and hyaluronic acid (HA) by using the layer-by-layer method. HA is able to target cancer ...
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Modulation of telomerase and signal transduction proteins by Hexyl-ALA-Photodynamic Therapy (PDT) in human doxorubicin resistant cancer cell models
30 January 2012
Ellie S.M. Chu, Christine M.N. Yow
Summary: Aims: This study employed a doxorubicin resistant (MES-SA-Dx5) human uterine sarcoma cell line and its counterpart (MES-SA), to elucidate the efficacy of aminolevulinic acid-hexylester (hexyl...
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Treatment of Kimura disease with photodynamic therapy: A case study
16 January 2012
Syedda Abbas, Waseem Jerjes, Tahwinder Upile, Anna Vincent, Colin Hopper
Summary: We report on the application of photodynamic therapy (PDT) in the management of Kimura disease. A 58-year-old Asian male was offered this modality to assess the possibility to control disease...
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Evaluation of collagen alteration after topical photodynamic therapy (PDT) using second harmonic generation (SHG) microscopy – in vivo study in a mouse model
16 January 2012
Ting Lv, Zu-Fang Huang, Hong-Wei Wang, Ju-Qiang Lin, Guan-Nan Chen, Xi-Wen Chen, Rong Chen, Zheng Huang, Xiu-Li Wang
Summary: Topical photodynamic therapy (PDT) mediated by 5-aminolevulinic acid (ALA) has been used for the treatment of age-related skin lesions for therapeutic or cosmetic purposes. The modulation of ...
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Comparison of cryotherapy and photodynamic therapy in treatment of oral leukoplakia
16 January 2012
Aleksandra Kawczyk-Krupka, Jadwiga Waśkowska, Agnieszka Raczkowska-Siostrzonek, Anna Kościarz-Grzesiok, Sebastian Kwiatek, Dariusz Straszak, Wojciech Latos, Rafał Koszowski, Aleksander Sieroń
Summary: Oral leukoplakia is a pre-malignant lesion of the oral mucosa. The aim of this study is to compare the curative effects of photodynamic therapy and cryotherapy in the treatment of oral leukop...
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